Stretch Responses of Cutaneous RA Afferent Neurons in Mouse Hairy Skin
نویسندگان
چکیده
منابع مشابه
Stretch responses of cutaneous RA afferent neurons in mouse hairy skin.
Rapidly adapting (RA), stretch-sensitive neurons were recorded in vitro, using an isolated preparation of skin and nerve from mouse hindlimb. The skin was stretched uniaxially using a pseudo-Gaussian noise stimulus. Loads and displacements were recorded as were spike responses of single RA afferent neurons. The goal was to determine what components of the mechanical stimulus were associated wit...
متن کاملStretch sensitivity of cutaneous RA mechanoreceptors in rat hairy skin.
Twenty-five rapidly adapting mechanoreceptor afferents were recorded in an in vitro preparation of rat skin and nerve. Single units were recorded while the skin was subjected to dynamic uniaxial stretch using a pseudo-Gaussian noise (PGN) input waveform. Force was the controlled variable in stretch stimuli. Measured loads and displacements were used to calculate tensile stresses, strains, and t...
متن کاملResponses of rapidly adapting afferent neurons to dynamic stretch of rat hairy skin.
Twenty-four rapidly adapting (RA) cutaneous afferents were recorded from a preparation of isolated, innervated hairy skin from the rat hindlimb for the purpose of identifying the mechanical variables associated with the initiation of afferent discharge. Neurons were studied while the skin was stretched dynamically along a single direction with the use of a linear actuator and a feedback control...
متن کاملRat cutaneous RA afferents activated by two-dimensional skin stretch.
Skin develops biaxial stresses and strains when stretched. Rapidly adapting cutaneous mechanoreceptor neurons are known to be stretch sensitive, yet in the past, they have been studied using stretch stimuli applied along only a single direction. In this study, cutaneous rapidly adapting mechanoreceptors were studied in preparations of isolated skin in which the skin was stretched dynamically us...
متن کاملProperties of Mouse Cutaneous RA Afferents : Relationship to Skin Viscoelasticity
When skin is stretched, stimuli experienced by a cutaneous mechanoreceptor neuron are transmitted to the nerve ending through the skin. In these experiments, we tested the hypothesis that the viscoelastic response of the skin influences the dynamic response of cutaneous rapidly adapting (RA) neurons. Cutaneous RA afferent neurons were recorded in 3 species of mice (Tsk, Pallid, and C57BL6) whos...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2002
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00909.2002